Iobenguane i 131
Azedra (iobenguane i 131) is a small molecule pharmaceutical. Iobenguane i 131 was first approved as Iobenguane sulfate i 131 on 1994-03-25.
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Brand Name | Status | Last Update |
|---|---|---|
| adreview | New Drug Application | 2024-01-10 |
Indications
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Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
IOBENGUANE I-131, AZEDRA, PROGENICS PHARMS INC | |||
| 2025-07-30 | ODE-204 | ||
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Clinical
Clinical Trials
54 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroblastoma | D009447 | EFO_0000621 | — | 1 | 1 | — | — | 1 | 3 |
| Neoplasms | D009369 | — | C80 | — | 1 | — | — | — | 1 |
| Neuroectodermal tumors | D017599 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pheochromocytoma | D010673 | — | — | — | — | — | — | 1 | 1 |
| Paraganglioma | D010235 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Iobenguane i 131 |
| INN | iobenguane (131i) |
| Description | 2-[(3-iodophenyl)methyl]guanidine is an organoiodine compound. |
| Classification | Small molecule |
| Drug class | iodine-containing contrast media |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | N=C(N)NCc1cccc([131I])c1 |
Identifiers
| PDB | — |
| CAS-ID | 77679-27-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1615779 |
| ChEBI ID | — |
| PubChem CID | 60860 |
| DrugBank | DB06704 |
| UNII ID | Q461L7AK4R (ChemIDplus, GSRS) |
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146 adverse events reported
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